Zeynep Kusku-Kiraz
Turkey
Research Article
The Association of Glycemic Markers with Plasma Adipocytokine Levels in Women with Gestational Diabetes
Author(s): Nida Oztop, Zeynep Kusku-Kiraz, Elmire Dervisoglu, Nevin Dinccag and Sema GencNida Oztop, Zeynep Kusku-Kiraz, Elmire Dervisoglu, Nevin Dinccag and Sema Genc
Introduction: Alterations in the synthesis of cytokines have been demonstrated in gestational diabetes (GDM), but the association of cytokines with short- and long-term glycemic markers has not been defined clearly. In this study, the variations in the plasma levels of visfatin, TNF-α, IL-1β, IL-6, and IL-10 were investigated and theirassociations with glycemic markers -HbA1C, fructosamine, 1,5-anhydro-D-glucitol (1,5-AG), and continuous glucose monitoring system (CGMS) parameters were evaluated. Material and methods: 33 pregnant women with GDM, and 20 pregnant women without any maternal and fetal disorder were comprised in the study. Three of the 33 women diagnosed with GDM required insulin therapy were excluded from the study. The visfatin, TNF-α, IL-1β, IL-6 and IL-10 and 1,5-AG were determined by ELISA. HbA1C% and fructosamine were also evalu.. View More»
