Soo-Kyoung Choi
Tanzania
Editorial
Endoplasmic Reticulum Stress and Microvascular Endothelial Dysfunction in Diabetes
Author(s): Modar Kassan, Maria Galán, Soo-Kyoung Choi and Khalid MatrouguiModar Kassan, Maria Galán, Soo-Kyoung Choi and Khalid Matrougui
Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia, due to deficiency in insulin or insulin resistance, and represents a major cause of morbidity and mortality in contemporary societies [1,2]. According to the world health organization (WHO), more than 285 million people worldwide suffered from diabetes of which 4 million died in 2010. The prevalence is expected to enhance to 380 million by 2030. Genetic and environmental factors associated with life style such as unhealthy diet, physical inactivity, harmful use of alcohol and tobacco, and obesity contribute to the increasing incidence of diabetes. The situation becomes extremely critical since type 1 and type 2 diabetes compromise the cardiovascular homeostasis. Based on the report of WHO and clinical studies, the direct cause of death for 80 % of diabetic patients is cardiovascular diseases. Studies in h.. View More»
