Shantal G Kamat
India
Research Article
Evaluation of Antioxidant Potential of Clarias Batrachus Oil in Alloxan Induced Diabetic Mice (Mus Musculus)
Author(s): Shantal G Kamat and Ramaballav RoyShantal G Kamat and Ramaballav Roy
Introduction: Diabetes mellitus is a chronic disorder in human and responsible for different complications and also causes mortality and morbidity. Long chain fatty acids influence inflammation through a variety of mechanisms; many of these are mediated by, or at least associated with, changes in fatty acid composition of cell membranes. Hence the present study was performed to investigate the effect of fish oil extracted from Clarias batrachus which is a good source of PUFA n-3 among freshwater species on alloxan-induced diabetic mice. Material and method: Alloxan was administered at repetitive doses (100 mg/kg b.wt after every 5th day for a period of one month to induce diabetes in mice. Along with alloxan injection, 10% Clarias fish oil was supplemented to diabetic mice for a period of one month. Analysis of basic antioxidant and lipid peroxidation parameters in serum, liver, kidne.. View More»
