Randa Ahmed Ibrahim
Egypt
Research Article
Effect of Platelet Rich Plasma (PRP) Injection on the Endocrine Pancreas of the Experimentally Induced Diabetes in Male Albino Rats: A Histological and Immunohistochemical Study
Author(s): Nashwa Fathy El-Tahawy, Rehab Ahmed Rifaai, Entesar Ali Saber, Saadia Ragab Saied and Randa Ahmed IbrahimNashwa Fathy El-Tahawy, Rehab Ahmed Rifaai, Entesar Ali Saber, Saadia Ragab Saied and Randa Ahmed Ibrahim
Introduction: Diabetes mellitus is a global problem and several restoration approaches have been developed to induce beta (β) cells regeneration. Platelet rich plasma (PRP) is an autogenous and economical source of growth factors which nowadays used in the tissue repair.
Aim: To test the hypothesis that PRP could play a role in the improvement of the structural changes occurred in the endocrine pancreas of experimentally- induced diabetic rats and the possible mechanisms through which PRP induced its effects to shed a light on the possible use of such application in the clinical field.
Material and methods: Sixty male albino rats were used; 20 for obtaining the PRP and 40 were divided into 4 equal groups (10 rats each): control, PRP-group, diabetic group, PRP/diabetic group. Diabetes was induced by single intra-peri.. View More»
