Ramesh C Saxena
India
Research Article
Evaluation of Anti-Hyperglycemic Activity of Adiantum Philippense Linn, a Pteridophyte in Alloxan Induced Diabetic Rats
Author(s): Tania Paul, Biswadeep Das, Kishori G Apte, Suchitra Banerjee and Ramesh C SaxenaTania Paul, Biswadeep Das, Kishori G Apte, Suchitra Banerjee and Ramesh C Saxena
To evaluate the potential of Adiantum philippense Linn in hyperglycemia induced by alloxan monohydrate, ethanolic and aqueous extracts of the fern, Adiantum philippense were assessed at two dose levels of 500 mg/kg and 250 mg/kg (p.o) respectively. Both the extracts treated groups at two doses exhibited significant hypoglycemic effect when compared to standard drug, glibenclamide and disease control group at an interval of 14 days which is evident from Plasma Glucose levels and Oral Glucose Tolerance Test (OGTT) values.
The serum parameters for kidney functioning like Urea, Creatinine, and lipid profile like Triglycerides, Cholesterol and HDL-cholesterol along with liver enzymes like SGPT and SGOT were assessed which favoured the potential of the fern in causing anti-hyperglycemia. At the end of 14 days study, the levels of liver glycogen of the rats of all the groups were e.. View More»
