Niketan Laner D’Souza
India
Research Article
Enhancing the Activity of Peroxisome Proliferator- Activated Receptors
(PPAR) Activity through Natural Ligand Binding in Diabetes: Substantial
Computational Approach
Author(s): Lakshmi Huttada, MB Hiremath and Niketan Laner D’SouzaLakshmi Huttada, MB Hiremath and Niketan Laner D’Souza
Background: Traditional medicines have been potential in regulating blood glucose control, leading to herbal treatment to manage diabetes from long time. Diabetes is proving to be a major problem throughout the world in the recent years. In spite of synthetic medications available in the market, to reduce the ill effects of diabetes and its secondary complications, herbal formulations are preferred due to less side effects and low cost. Objective: The present study attempts in studying antidiabetic property of an unexploited plant, Exacum pedunculatum, belonging to Gentianaceae family, from the Western Ghats of India. Methodology: The dried plant material was subjected to extraction for isolating compounds which was purified to obtain biguanide compound and screened in silico to study the antidiabetic nature of the compound. Result: Promising phytochemicals are present in the extract .. View More»
