Ndiaye M
Senegal
Research Article
Toxic Epidermal Necrolysis in Senegal, 2005 Through 2015: Epidemiological and Drug Etiology
Author(s): Diallo M, Diop A, Diadie S, Diatta BA, Ndiaye M, Seck B, Faye MF, Ly F, Niang SO and Kane ADiallo M, Diop A, Diadie S, Diatta BA, Ndiaye M, Seck B, Faye MF, Ly F, Niang SO and Kane A
Introduction: The aim of this study was to determine the epidemiological and drug etiology of the toxic epidermal necrosis (TEN) or Lyell’s syndrome in our Department.
Patients and Methodology: Medical records of all admitted patients for TEN over an eleven-year period were analysed retrospectively.
Findings: We collected 251 cases of drug-induced skin reactions, representing 0.3% of medical visits and 0.7% of admissions. On average, 5 patients suffering from TEN were hospitalized every year. They mostly consisted of young women with a mean age of 35 ± 19.71 years and a sex-ratio of 0.5. About half of patients have been evacuated by road from the various provinces of the country, sometimes over 500 km away. The culprit drug was prescribed by a nurse of an infirmary in 35% of the cases. A self-medication with.. View More»
