Masami Tanaka
School of Medicine,
35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582
Japan
Research Article
Relationship between Urinary Pentosidine Concentration and Vascular Complications in Type 2 Diabetic Patients
Author(s): Masami TanakaMasami Tanaka
Objective: We examined the relationship between urinary pentosidine concentration and vascular complications in patients with type 2 diabetes in order to investigate the pathophysiological roles of pentosidine. Methods: We performed a cross-sectional study in 119 Japanese patients with type 2 diabetes. The correlation of urinary pentosidine concentration with age, diabetes duration, HbA1c and blood glucose levels was investigated. Urinary pentosidine concentration was compared between patients with and without diabetic microvascular complications (retinopathy, nephropathy, and neuropathy), and macrovascular disease. Results: Urinary pentosidine concentration showed a significant positive correlation with age and duration of diabetes. However, it did not correlate with HbA1c, fasting plasma glucose, and postprandial plasma glucose. Patients with diabet.. View More»
