Martina Persson
Karolinska University Hospital, Karolinska Institutet,
Stockholm
Sweden
Research Article
Effect of Parity on Pregnancy Outcome in Women with Type-1 Diabetes – A Swedish Population-based Study
Author(s): Martina Persson and Dharmintra PasupathyMartina Persson and Dharmintra Pasupathy
Aim: Women without diabetes are at increased risk of pregnancy complications in their first pregnancy. The aim of this study was to investigate if the risk of adverse pregnancy outcomes also differs with parity in women with type 1 diabetes (T1DM). Methods: Population based prospective cohort study of all singleton pregnancies to women with T1DM (n=4092) in Sweden between 1998 and 2007. Data was derived from the Swedish Medical Birth Registry. Outcomes of interest were preeclampsia (PE), gestational hypertension (GH), major malformation, perinatal mortality (PMR), preterm delivery, large for gestational age (LGA), small for gestational age (SGA) and neonatal death. Logistic regression analysis was used to obtain odds ratios (OR) for adverse outcomes in relation to parity. Interaction tests were performed to compare the association of interest in non-diabetic pregnancies. Results: The .. View More»
