Mariano Fernández-Fairén
Spain
Research Article
Analysis of the Results on Perioperative Blood Loss after a Total Knee Arthroplasty Employing Tranexamic Acid before or after Inflating the Tourniquet
Author(s): Ana Torres, Mariano Fernández-Fairén and Daniel Hernández VaqueroAna Torres, Mariano Fernández-Fairén and Daniel Hernández Vaquero
Introduction: Tranexamic acid has showed its good results reducing blood loss in total knee arthroplasties. It has also probed being cost-effective (red cell concentrate: 350 euros/ TXA vial 3, 05 euros) but it remains not being clear at what time during the surgery we have to administrate it. In this prospective, randomized study, we have investigated the effects of the use of tranexamic acid before or after inflating the tourniquet on blood loss, transfusion needs and thromboembolic complications after implanting a total knee arthroplasty. 120 patients were selected and assigned randomly in two groups: tranexamic acid employed before inflating (group 1) or just before deflating the tourniquet (Group 2).
Methods and Materials: From May 2011 to May 2012, 80 patients (38 males, 42 females; aged 64-81 years, mean age 69, 2years) underwent to a.. View More»
