Li Wei
China
Research Article
Effect of PNS on Mobilizing Bone-marrow Mesenchymal Stem Cells in Rats
Author(s): Zhang Baoxia, Zhang Jinsheng, Du Meimei, Wang Xiaoya and Li WeiZhang Baoxia, Zhang Jinsheng, Du Meimei, Wang Xiaoya and Li Wei
Objective: To investigate the effects of panax notoginseng saponins on mobilizing bone marrow mesenchymal stem cells after cerebral infarction so as to provide experimental basis for Huoxue Huayu Decoction (HXHYD) that is promoting the blood flow and removing blood stasis.
Methods: Apart from the normal group, all of the remaining rats must survive the improved Zea-Longa middle cerebral artery occlusion (MCAO) modeling method; all standard rats were randomly divided into four groups. The first group designated as control group was administered with normal saline by gavage every day. The second, third and fourth groups designated as drug groups were administered respectively with Xuesaitong soft Capsule (ingredients dissolved in normal saline) in 20, 40 and 60 mg/ml body weight/day (low-dose group, mid-dose group and high-dose group). The tre.. View More»
