Koichi Hirai
Japan
Research Article
Glycated Albumin, Rather than Hba1c, Reflects Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus
Author(s): Shinya Morita, Soji Kasayama, Reiko Deguchi, Koichi Hirai, Kosuke Mukai, Yoshihiko Utsu, Satoru Sumitani, Bunzo Sato and Masafumi KogaShinya Morita, Soji Kasayama, Reiko Deguchi, Koichi Hirai, Kosuke Mukai, Yoshihiko Utsu, Satoru Sumitani, Bunzo Sato and Masafumi Koga
Background: It has recently been shown that glycated albumin (GA) has some different aspects from HbA1c as an indicator of chronic glycemic control, besides it reflects shorter periods of glycemia. In this study, we investigated whether both indices of chronic glycemia are differently influenced by diabetic duration and diabetic vascular complications.
Methods: The present study included 63 patients with type 2 diabetes mellitus (40 men, 23 women) in whom HbA1c and GA were simultaneously measured every other month during a year. Annual mean levels of HbA1c, GA, and the GA/HbA1c ratio were determined, and the associations of these values with diabetes duration, diabetic retinopathy, and diabetic nephropathy were analyzed.
Results: Annual mean levels of the GA/HbA1c ratio were significantly correlated with diabetes d.. View More»
