Ken Terui
Hirosaki University Graduate School of Medicine,
5 Zaifu-cho, Hirosaki
Japan
Research Article
Post-Saline Infusion Plasma Aldosterone Concentrations are Well Correlated with the Lateralized Ratio of Adrenal Venous Sampling in Patients of Primary Aldosteronism
Author(s): Yuko Tsushima, Ken Terui, Koshi Makita, Yuko Asari, Noriko Ishigame, Yuki Nakada, Aya Sugiyama, Shingo Murasawa, Satoshi Yamagata, Yutaka Watanuki, Shinobu Takayasu, Takeshi Nigawara, Kazunori Kageyama and Makoto DaimonYuko Tsushima, Ken Terui, Koshi Makita, Yuko Asari, Noriko Ishigame, Yuki Nakada, Aya Sugiyama, Shingo Murasawa, Satoshi Yamagata, Yutaka Watanuki, Shinobu Takayasu, Takeshi Nigawara, Kazunori Kageyama and Makoto Daimon
Objective: Adrenal venous sampling (AVS) is the most reliable test to distinguish between unilateral and bilateral primary aldosteronism (PA). However, AVS is invasive, risky, and expensive, and alternative diagnostic methods are desirable. This study aimed to investigate the diagnostic power of saline infusion test (SIT) to distinguish between unilateral and bilateral PA.
Design: Retrospective database analysis.
Subjects and Methods: We selected 111 patients with PA diagnosed by confirmatory tests who underwent both SIT and successful AVS. Thirty-two patients had lateralized ratio (LR) over 4.0 and 79 patients had LR less than 4.0. Multiple regression analysis and receiver operating characteristic (ROC) analysis were used to examine whether the SIT had good diagnostic power to distinguish between patients .. View More»
