Jyoti Goutam
Laboratory of Mycopathology and Microbial Technology, Center of Advance Study in Botany,
Varanasi-221 005, Uttar Pradesh
India
Research Article
Isolation and Identification of Antibacterial Compounds Isolated from
Endophytic Fungus Emericella qaudrilineata
Author(s): Jyoti Goutam, R N Kharwar, Vinod Kumar Tiwari, Amrita Mishra and Shweta SinghJyoti Goutam, R N Kharwar, Vinod Kumar Tiwari, Amrita Mishra and Shweta Singh
Present work is directed toward the isolation and identification of biological active (antimicrobial) compound from metabolite extracted from endophytic fungus Emericella qaudrilineata (Accession number KC662361). Crude extracted from endophytic fungus Emericella qaudrilineata possessing antibacterial activity was subjected to bioassay guided fractionation in which toluene fraction exhibited maximum antibacterial activity against Staphylococcus aureus (gram positive) and Aeromonas hydrophilla (gram negative) respectively. Sequentially compounds fractionated from ethyl acetate and hexane also shown feeble antibacterial activity. This reveals that toluene fraction contain active principle of antimicrobial interest. In continuation to above experiment, major active fractions were analyzed with the help of gas chromatography mass .. View More»