Heleen M. den Hertog
Netherlands
Research Article
Newly-Diagnosed Disturbed Glucose Metabolism is Associated with Atherosclerosis in Patients with Transient Ischemic Attack or Ischemic Stroke
Author(s): Susanne Fonville, Anouk C van Dijk, Taihra Zadi, Evita G van den Herik, Hester F Lingsma, Peter J Koudstaal, Aad van der Lugt and Heleen M. den HertogSusanne Fonville, Anouk C van Dijk, Taihra Zadi, Evita G van den Herik, Hester F Lingsma, Peter J Koudstaal, Aad van der Lugt and Heleen M. den Hertog
Objective: Newly-diagnosed disturbed glucose metabolism is highly prevalent in non-diabetic patients with transient ischemic attack (TIA) or ischemic stroke, and increases the risk of recurrent stroke. Diabetes mellitus is associated with atherosclerosis. We aimed to assess whether newly-diagnosed disturbed glucose metabolism is associated with atherosclerosis as well.
Research design and methods: Patients with a recent TIA or ischemic stroke were classified in three groups based on glucose levels and use of antidiabetic drugs. Pre-existent diabetes mellitus was defined as the use of antidiabetic drugs prior to the event. Newly-diagnosed disturbed glucose metabolism was defined as two or more disturbed glucose tests: fasting plasma glucose level ≥ 5.6 mmol/L, 2-hour post-load glucose leve.. View More»