Brendolan A
Italy
Case Report
Urinary Neutrophil Gelatinase-Associated Lipocalin (uNGAL) in High Altitude: A Case Study
Author(s): Scalzotto E, Corradi V, Brendolan A, Orrasch M, Fortunato A, Giavarina D and Ronco CScalzotto E, Corradi V, Brendolan A, Orrasch M, Fortunato A, Giavarina D and Ronco C
Introduction and Aims: Medical problems occur at high altitude. The classical physiological responses to high altitude include hyperventilation, polycythemia and hypoxiemia. Type 1 diabetes (T1D) can participate in extreme altitude mountaineering. The prevalence of acute kidney injury (AKI) at high altitude is not known. We studied the renal function, by urinary Neutrophil gelatinase-associated lipocalin (uNGAL) in high altitude, as a promising biomarker for early detection of AKI.
Methods: The 2012 ADIQ Expedition team included 4 male Caucasians participants (prt): two with T1D and two non-diabetics. Urine Glucose, Protein, Urobilinogen, pH, Specific Gravity, Blood, Ketones, Nitrite and Leucocytes were determinated on-site by Aution Sticks. The uCreatinine and uUrea were measured by F360 analyzer. uNGAL concentration was measured by the ARCHITECT urine NGAL assay. Microalbu.. View More»
