Biswajit Das
India
Research Article
Glycemic Control and Cardiovascular Outcomes in Diabetes
Author(s): Biswajit Das and Trinath Kumar MishraBiswajit Das and Trinath Kumar Mishra
While type 1 Diabetes Mellitus (DM) is characterized by insulin deficiency due to pancreatic beta cell destruction, type 2 DM is characterized by a state of long standing insulin resistance (IR), compensatory hyperinsulinemia and varying degrees of elevated plasma glucose (PG), associated with clustering of cardiovascular (CV) risk and development of macrovascular disease prior to diagnosis of DM. Coronary artery disease (CAD) accounts for 70% of mortality and morbidity in patients with diabetes.
Studies made in diabetes care have helped prevent or reduce microvascular complications in type 1 and 2 diabetes. However the same cannot be said about macrovascular disease.
Despite all data concerning the association of diabetes and cardiovascular disease (CVD), the exact mechanism by which diabetes is linked to atherosclerosis is incompletely understood, this is especia.. View More»
