Bijaya Mohanty
Tata Main Hospital,
Jamshedpur
India
Review Article
Choosing the Best Oral Diabetic Agents in T2 Diabetes Mellitus-Physicians Challenge
Author(s): Bijaya MohantyBijaya Mohanty
The therapeutic armamentarium of oral diabetic agents has expanded its horizon from sulfonylureas in 1995 the only drug available for treating type 2 diabetes mellitus at that time to eleven classes of oral diabetes agents at present ranging from biguanides, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, alpha glucosidase inhibitors and sodium-glucose cotransporter (SGLT2) inhibitors. Despite the availability of so many options glycemic control remains suboptimal posing a real challenge for the clinicians to choose the best amongst them in treating type 2 diabetes mellitus.
Before choosing the drugs it is important to know the recommendations of glycemic goals in adults. A reasonable glycosylated hemoglobin (A1C) goal in adult is <7%. However all glycemic goals should be individualized and customized. Setting individual glycemic goals needs consideration o.. View More»
