Bela Melegh
Hungary
Review Article
Triglyceride Level Affecting Shared Susceptibility Genetic Variants in Type 2 Diabetes Mellitus
Author(s): Katalin Sümegi, BelaI. Melegh, Anita Maasz, Peter Kisfali, Judit Bene and Bela MeleghKatalin Sümegi, BelaI. Melegh, Anita Maasz, Peter Kisfali, Judit Bene and Bela Melegh
Type 2 diabetes mellitus represents a significant global health problem contributing to a considerably increased atherosclerotic burden and cardio- and cerebrovascular risk. Type 2 diabetes mellitus has high incidence and prevalence affecting both genders at any time of life worldwide. Presence of diabetes related phenotypes may represent risk for other metabolic diseases, cardio-, and cerebrovascular disorders, as well. The etiology of type 2 diabetes mellitus is complex; several environmental-, and genetic factors have been identified, which can contribute to the pathogenesis of the disease. Nowadays, numerous genetic loci have been shown to associate with type 2 diabetes mellitus and other diabetic traits, and the number of the identified susceptibility variants is expected to still grow due to rapidly developing field of candidate gene -, linkage-, and genome-wide association stud.. View More»
