Alan D Widgerow
Irvine and Chief Medical Officer Alastin Skin Care, 3129 Tiger Run Court #109, Carlsbad, CA 92010
Tanzania
Case Report
Histological Changes Associated with Extracellular Matrix-Remodeling Topical Therapy
Author(s): Antoanella Calame and Alan D WidgerowAntoanella Calame and Alan D Widgerow
Introduction: An innovative skincare product line incorporating a proprietary blend of selected peptides and botanicals formulation has been developed with the aim of preparing skin surfaces for rejuvenating procedures and for their long-term maintenance. The premise is to clear the extracellular matrix (ECM) of accumulated waste products improving cellular ECM cross talk enabling efficient collagenesis and elastogenesis to follow.
Methods: To validate this scientific narrative and examine efficacy without the use of rejuvenating devices, we have undertaken a series of histological examinations in 5 subjects in their 60s assessing changes following isolated topical application of product to the skin.
Results: From a histological perspective, our findings showed significant changes within the ECM, with new collagen format.. View More»
