Research Article
Diabetes Mellitus and Neuromuscular Blockade: Review
Author(s): Armendariz-Buil Ignacio, Lobato-Solores Felix and Aguilera-Celorrio LucianobArmendariz-Buil Ignacio, Lobato-Solores Felix and Aguilera-Celorrio Lucianob
Introduction and objectives: International Diabetes Federation (IDF) estimates that worldwide there are 415 million adults aged 20-79 with diabetes mellitus (DM). Although diabetes mellitus (DM) is a highly prevalent disease, only a handful of studies have examined the neuromuscular function in diabetic patients. Even more surprising is this data, if we think that neuromuscular blockade (NMB) is an essential part in the induction and maintenance of general anesthesia. NMB is induced by neuromuscular blocking agents (NMBA). The aim of this review is to update the knowledge of neuromuscular blockade in diabetes mellitus and its implications in clinical practice. Material and Methods: Studies on neuromuscular function in DM were reviewed to establish the pathophysiological bases. Subsequently, all the literature that included clinical studies on neuromus.. View More»
