Lalchamliani Khiangte, Th.I.Devi, W.G.Singh and T.R Singh
Scientific Tracks Abstracts: Anaplastology
The study carried out to find out the association of thyroid hormone and most common discoloration of skin, Vitiligo in North-East India which has become a cosmetic problem. It is a prospective randomised controlled study where 125 patients attending Dermatology OPD in RIMS were enrolled. Analysis of serum total Triiodothyronine (tT3), total Thyroxine(tT4), thyrotropine(TSH) were estimated by ELISA using commercially available kit manufactured by Monobind Inc.Lake forest, CA,USA for quantitative determination. And find out its concentration in Human Serum or Plasma. Biochemical abnormality especially clinical hypothyroidism (37.78%) is predominantly maximum followed by clinical hyperthyroidism (10%) which is satistically significant(P<0.05) with a chi-square value of 10.08. Females 32(35.56%) are having clinical thyroid dysfunction more than males 21(23.33%) which is statistically significant (P<0.05) with a chi-square value of 5.68. Again, distribution and classification of vitiligo patients with reference to thyroid disorder, whether clinical or biochemical or immunological shows that 87.78% have thyroid involvement with 5.56% subclinical hypothyroidism. Only 12.22% of vitiligo patients are not associated with any thyroid disorder.Nonetheless, there exist a correlation between the extent of skin depigmentation and level of thyroid disorder. Therefore, early routine screening of thyroid parameters TSH,T3,T4 is a must for any skin discoloration will make Clinicians and Dermatologist to achieve at the earliest diagnosis before it becomes a cosmetic problem.
Lalchamliani khiangte has completed MBBS from Lady Hardinge Medical College, New Delhi. MD Biochemistry from Regional Institute of Medical Sciences. Worked in HIV field as ART MO, finished ICU &ICCU course both in paediatrics and adult from N.Delhi. Established her own ZO DRIM (Zo Diagnostic Research Institute and Medicare) and Zo Diagnostic where many researches are being carried out.
