Mark Feitelson
Temple University, USA
Posters & Accepted Abstracts: J Steroids Hormon Sci
Natural compounds have been shown to be useful for the treatment of cancers in preclinical models, but given that cancers are multi-step, efforts have focused upon formulating combination therapies that target early stage tumors in a hypoxic environment, block epithelial-mesenchymal transition (EMT) during tumor metastasis, inhibit uncontrolled cell cycle progression and target cancer stem cells to help prevent tumor relapse. Combinations of natural compounds will also be presented that are likely to be useful against estrogen dependent breast cancer as well as androgen dependent and independent stages of prostate cancer. Results will summarize what is likely to be the most important natural compounds and molecular targets that will results in arrested proliferation during tumor pathogenesis as well as recommendations for the application of natural compound combinations in preclinical models and in human clinical trials.
Email: feitelso@temple.edu
