Teagan Adamson
Scientific Tracks Abstracts: J Diabetes Metab
The Multiplexed Diabetes Management (MDM) device and concept is basically extending the current technology of diabetes care to include other markers of interests. Th e team is a mixed background of electrical, biomedical and computer science engineering undergraduates, graduates students, and faculty. Th e basic operation of the proposed device would be similar to current self-monitoring blood glucose devices. Th e user simply pricks their fi nger for a small volume of blood, which travels through a capture fl uidics system that lyses part of the sample while electrochemically analyzing it for multiple markers currently involved in diabetic care and research. Th e analysis retrieved on the markers, which exist in infl ammatory, metabolic, and immunological pathways will, further aid in daily diabetes care. Th ese markers include: glucose, insulin, HbA1c, 1,5-Anhydroglucitol, and Glycated Albumin. Th e underlying technological development of MDM, the simultaneous detection of fi ve diff erent markers, comes from a breakthrough development in electrochemical sensing and instrumentation. Th e transformative detection scheme is a modifi ed electrochemical impedance spectroscopy (EIS) technique developed in the La Belle Lab for tuning markers responses (frequency shift ) away from one another. Instead of using a simple DC voltage to induce an enzymatic current fl ow, this novel technique uses mixed frequency AC signals to perturb enzymes and antibodies specifi c for these fi ve markers, simultaneously. Once deconvoluted, these signals can show a correlation of the impedance measured to concentrations of the targets in blood.
Teagan Adamson is completing her B.S.E. degree in Biomedical Engineering with a minor in Chinese from Arizona State University. She is the team leader of the MDM Team in the La Belle Lab. Her portion of the project includes development of the electrochemical impedance spectroscopy based detection of glucose and 1,5-anhydroglucitol. She was a senator for the Ira A. Fulton School of Engineering, and is heavily involved in the Engineering Student Council at ASU. In addition she is a member of Theta Tau, a professional Engineering Fraternity, and is conducting research on her undergraduate thesis for Barrett, the Honors College.
