S Garba, K Ado, L Salihu and B B Alhaji
Accepted Abstracts: Nat Prod Chem Res
Thirteen species of medicinal plants commonly found in Northern Nigeria were extracted using different solvents of extraction and subjected to bioscreening study to detect cytotoxic activity using brine shrimp lethality and Fundulopanchax gardneri tests. The plants include Schwenkia americana, Aristolochia albida, Cassia arereh, Taminalia mollis, Hymenocardia acida, Carissa edulis, Daniella oliveri, Cussonia arborea, Mangifera indica, Uvaria chamae, Pseudocedrella kotchyii, Tamarindus indica and Nebouldia laevi. A correlation coefficient of 0.964 (P<0.05) obtained from the data of both tests suggest that there is a positive correlation between the two variables. T-test of -0.808, (P>0.05) suggests that there is no significant difference between the two variables. This shows that the two results are in consonance suggesting that Fundulopanchax gardneri test can be used as a preliminary method for assessing the cytotoxicity of natural products.
