Mohammad Akbar Dar and Mubashir Hussain Masoodi
Accepted Abstracts: Nat Prod Chem Res
To evaluate the antioxidant actions of Portulaca oleracea Linn from Kashmir region, different standard assays were used. Extraction was carrying out using chloroform, methanol (hot extraction) and water (cold extraction).The percentage inhibition of DPPH free radical scavenging was 75.43%, 65.9% and 35.10% by methanol, aqueous and chloroform extracts respectively at the concentration of 500μg/mL. The percentage inhibition of nitrous oxide radical scavenging was 81.1%, 69.7% and 43.26% by methanol, aqueous and chloroform extracts respectively at the concentration of 500μg/mL. Also methanol extract shows highest reducing power compared to aqueous and chloroform extracts and was found to increases with concentration. The total phenolic content was found to be 60 ? 0.19, 198 ? 1.1 and 301 ? 1.2 mg/g in chloroform, aqueous and methanol extracts respectively and the total flavonoid content was found to be 90 ? 0.02, 186 ? 1.1 and 299 ? 1.2 mg/g in chloroform, aqueous and methanol extracts of Portulaca oleracea Linn respectively. The results indicate that methanol extract of Portulaca oleracea Linn from Kashmir region has good antioxidant activity and may be used for formulating some preparations for the treatment of different diseases associated with reactive oxygen species.
Mohammad Akbar Dar has completed his BSc, B Pharma and M Pharma (Pharmaceutical Chemistry) from University of Kashmir and is currently pursuing his PhD from Department of Pharmaceutical Sciences, University of Kashmir. He has been selected for a fellowship (Basic Science Research) by University Grants Commision. He has published more than 6 papers in reputed journals.
