General Medicine: Open Access

ISSN - 2327-5146

Aspects of depression prior to the onset of direct-acting antiviral therapy in patients diagnosed with chronic hepatitis C virus infection

22nd World Congress on Pharmaceutical Sciences and Innovations in Pharma Industry & 14th Euro-Global Conference on Infectious Diseases & 10th International Conference on Mental Health and Human Resilience

June 24-25, 2022 | WEBINAR

Andreea Florentina Stoenescu

Clinical Hospital of Infectious and Tropical Diseases, Romania

Posters & Accepted Abstracts: Gen Med (Los Angeles)

Abstract :

Introduction: Depression is a common condition reported in patients with chronic hepatitis C virus, with a prevalence of 1.5 to 4 times higher than patients with chronic hepatitis B virus. It affects the quality of life and leads to high costs of health care. Material and Method: Prospective study in a group of 30 patients diagnosed with chronic hepatitis C virus, naive in antiviral treatment, on which the Hamilton Depression Scale questionnaire was applied at the beginning of direct-acting antiviral therapy. Results: Of the 30 patients, 16 were female, with no discrepancy between the two genders. In the analyzed group, 22 patients are aged between 30-50 years, most of them come from urban areas (21), and the level of education was predominantly average (17). 9 of the patients in the past had risky behaviors (intravenous drug administration), and 13 had at least 1 tattoo one-third of patients received blood transfusions following the results of the questionnaire, 11 of the patients were classified as having a mild depression and 1 patient with a moderate level of depression. In patients with mild depression, the evolutionary stage of the disease represented by the degree of hepatic fibrosis was F0, F1 and F2. The patient with moderate depression had a degree of fibrosis F3. Regarding the first category, 3 of the patients were previously diagnosed with mental disorders and depressive syndrome and were on medication, and 2 were on antihypertensive treatment. The patient, who obtained the highest score after applying the Hamilton scale and also had F3, also had hypertension and diabetes. Conclusion: Depression remains one of the most common extra hepatic manifestations of chronic hepatitis C virus infection. Early diagnosis and appropriate treatment have a beneficial effect on both the quality of life and the progression of liver disease.
Recent publications :
1. Clinical picture of COVID19 - Emanoil Ceausu, Simin Aysel Florescu, Andreea Stoenescu. COVID-19 pandemic in Romania, Clinical and epidemiological aspects. Romanian Academy Publishing House 2020 ISBN 978-973-27-3253-3
2. A particular case of SARS-CoV-2 infection in twins - Andreea Florentina Stoenescu, Geta Vancea, Dana Ispas, Nicoleta Voicu-Parvu, Nicoleta Tudor, Gabriela Scurtu, Raluca Popescu, Claudia Chirila, Elena Sandu, Emanoil Ceausu, Simin-Aysel Florescu, , Romanian Journal of Infectious Diseases, Vol XXIV, Nr 2, 2021
3. Clinical-epidemiological and evolutionary aspects in the first 20 patients diagnosed with COVID-19 hospitalized in „Dr. Victor Babes“ Infectious and Tropical Diseases Clinical Hospital - Andreea Florentina Stoenescu, Alexandru Cosmin Marin, George Gherlan, Corneliu Petru Popescu, Sebastian Smadu, Ana Maria Veja, Adelina Dogaru, Filofteia Cojanu-Banicioiu, Nicoleta Voicu-Parvu, Luminita Ene, Petre Calistru, Emanoil Ceausu, Simin Florescu, Romanian Journal of Infectious Diseases, Vol XXIII, Nr 2, 2020
4. Radiological aspects in patients diagnosed with SARS-CoV-2 infection – a literature review - Maria Cristina Hoara, Andreea Florentina Stoenescu, Nedeea Duta, Petre Calistru, Emanoil Ceausu, Simin Florescu, Romanian Journal of Infectious Diseases, Vol XXIII, Nr 2, 2020
5. Epidemiological, clinical and progressive spectrum of measles cases admitted to „Dr. Victor Babes“ Clinical Hospital for Infectious and Tropical Diseases, Bucharest during the actual outbreak - GetaVancea, MD, Andreea Stoenescu, MD, Irina Ianache MD, Cristina Iordache MD, Eugenia Ungureanu MD, Carmen Apostol MD, Gh. Enache MD, Dana Ispas, MD, D. �?erban, MD, Roxana Cebuc, Alexandra Malciolu-Nica, Univ. Assist. Ana-Maria Dascalu, MD, Prof. Emanoil Ceau�?u, MD, PhD, Prof. Petre Iacob Calistru, MD, PhD – Romanian Journal of Infectious Diseases, Vol. XXI, Nr. 3, 2018.

Biography :

My name is Andreea Florentina Stoenescu, I am a resident doctor in my 5th year, in the specialty of Infectious and Tropical Diseases, in the Clinical Hospital of Infectious and Tropical Diseases ``Dr. Victor Babes`` from Bucharest, Romania. My areas of interest include pediatric infectious diseases but also tropical diseases and hepatitis. Currently I am working on Phd Thesis in the field of C virus hepatitis and my Master Degree programme in medical law.

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