Mohammad Saifuddin
Abdul Malek Ukil Medical College, Bangladesh
Keynote: J Diabetes Metab
Patients with Diabetes Mellitus (DM) are prone to develop infection, especially
Urinary Tract Infection (UTI) in comparison with non-diabetics. Due
to the emergence of Multidrug Resistant (MDR) uropathogenic strains, the
choice of antimicrobial agent is sometimes difficult. This study is designed to
reveal the distribution of uropathogens in diabetic patients and corresponding
sensitivity patterns and to correlate the microbiological results with various
clinical parameters. A nine-month retrospective review of 100 urine culture
reports of Diabetic patients from January 2015 to September 2015 from semiurban
multispecialty hospital of Feni, Bangladesh were analyzed. Only diabetic
patients were included in this study who were clinically diagnosed as UTI patients with a corresponding urine culture showing
a bacterial count of >105 CFU/ml. Out of 100 patients with UTI, 39 (39%) were male and 61 (61%) were female. Organisms
grown in urine culture were Escherichia coli (64) followed by Klebsiella (11), Proteus (7), Staphylococcus aureus (4), Pseudomonas
(4), Acinetobacter (3), Streptococcus (3), Enterococcus (2) and one each of Enterobacter and Fungi. Overall sensitivity pattern
in decreasing order of various commo nly used antibiotics were Meropenem (89%), Nitrofurantoin (86%), Amikacin (81%),
Ceftriaxone (68%), Cefuroxime (61%), Cefixime (39%), Quinolones (28%) and Amoxicillin (16%). The significance of the study
lies in the determination of common pathogens in diabetic patients with UTI and the resistance pattern of antibiotics so that
physicians and pharmacists get the proper information rationalizing the rational use of antibiotics.
References
1. Guariguata L, Whiting D R, Hambleton I, Beagley J, Linnenkamp U and Shaw J E (2014) Global estimates of diabetes prevalence for
2013 and projections for 2035. Diabetes Res Clin Pract.; 103(2): 137-49.
2. Patterson J E and Andriole V T (1997) Bacterial urinary tract infections in diabetes. Infect Dis Clin North Am.; 11(3): 735-50.
3. Schneeberger C, Kazemier B M and Geerlings S E (2014) Asymptomatic bacteriuria and urinary tract infections in special patient
groups: women with diabetes mellitus and pregnant women. Curr Opin Infect Dis.; 27(1): 108-14.
4. Patterson J E and Andriole V T (1997) Bacterial urinary tract infections in diabetics. Infect Dis Clin North Am.; 11(3): 735-750.
5. Boyko E J, Fihn S D, Scholes D, Abraham L and Monsey B (2005) Risk of urinary tract infection and asymptomatic bacteriuria among
diabetic and non-diabetic postmenopausal women. Am J Epidemiol.; 161(6): 557-564.
Mohammad Saifuddin is a young eminent Endocrinologist of Bangladesh who dedicated himself in service of humanity towards rural people of Bangladesh. He has received his MBBS from Dhaka Medical College at 2004 and obtained Fellowship in Medicine (FCPS) from Bangladesh College of Physicians and Surgeons in 2012 and passed MD (Endocrinology) from BIRDEM Academy at 2013. He had worked in Bangladesh Civil Service for the last 10 years and currently working as an Assistant Professor (Endocrinology) in Abdul Malek Ukil Medical College, Noakhali, Bangladesh. He has 14 publications in national and international level. His research interests are in diabetes and complications, adrenal disorders, osteoporosis, thyroid disorders and menstrual abnormalities.
E-mail: saifk56dmc@yahoo.com