Rizki Dwayana Putra
Andalas University School of Medicine, Indonesia
Posters & Accepted Abstracts: J Diabetes Metab
Diabetes mellitus (DM) is a metabolic disease that occurs due to abnormalities in insulin secretion, insulin action or both. African tea leaf extract (Vernonia amygdalina) had been investigated for diabetes therapy. The purpose of this study was to determine the effect of African tea leaf extract (Vernonia amygdalina) for decreasing blood glucose levels in alloxan-induced diabetic mice (Mus musculus). This experimental study using 15 mice, weighing 20-30 grams, were divided into three groups: Control group (K1), alloxan induction with (P) and without (K2) extract supplementation (200 mg bw/d). The results showed an increase in average fasting blood glucose levels in the K2 and P group after alloxan induction: 152.20 ± 15.304 mg/dl and 175.00 ± 44.435 mg/dl, respectively. After administering the extract for ten days, the average fasting blood glucose levels in P group were significantly decreased (100.60 ± 6.148mg/dl) compared to K2 group (435.80 ± 139.820 mg/dl). It could be concluded that Vernonia amygdalina extract supplementation decreased fasting blood glucose level.
Email: dwayanarizki@gmail.com
