Department of Biomedical Sciences, University of Buea, Cameroon
Research Article
Two New Cycloartenol and Some Pentacyclic Triterpenoids from Cameroonian Propolis (Ngaoundal, AD Region) and Evaluation of their Antimicrobial Activity
Author(s): Sakava Paul*, Tagatsing Fotsing Maurice*, Zeuko'o Menkem Elisabeth, Talla Emmanuel, Laurent Sophie, Celine Hénoumont, Vander Elst Luce, Awantu Fusi Angelbert, Atchadé Alex de Théodore and Mbafor Tanyi Joseph
The objective of this study was the isolation, the structure elucidation and the identification of chemical constituents from the n-hexane, the ethyl acetate (EtOAc) and the methanol (MeOH) extracts of a cameroonian propolis sample collected from Ngaoundal. Thirteen secondary metabolites belonging to cycloartane, ursane and oleananetype triterpenes were isolated and their structures were established by chemical tests and detailed spectroscopic analysis as cycloart-23(E)-en-3β,25-diol (1), cycloarta-7(E),23(E)-diene-3β,25-diol (2), cycloarta-23(E),25(26)-diene3β-ol (3), 25-pentoxy cycloart-23(E)-en-3β-ol (4), cycloartenol (5), 3β-hydroxyolean-12-en-18β-28-oic acid (oleanolic acid) (6), 3α-hydroxyoleanolic acid (3-Epi-oleanolic acid (7), 3β-hydroxyurs-12-en-18β-28-oic acid (ursolic acid) (8), 3α-hydroxyursolic acid (3-Epi-ursolic acid).. View More»
