Internal medicine, University clinic of Endoctinology, diabetes and metabolic disorders, North Macedonia
Research Article
Severe Hypertriglyceridemia and The Risk for Acute Pancreatitis Treated with Fluids and Rapid Insulin in Type 2 Diabetes and Non-Diabetic Patients
Author(s): Irfan Ahmeti*, Sash Jovanoska Misevska, Xhuliana Mihajlovska, Ivana Mladenovska Stojkoska, Sebajet Ahmeti Jakupi and Dragan Mijakoski
Introduction: High levels of triglycerides (TG) in the serum can cause acute pancreatitis. Contrarily, there is a proven benefit of the rapid decrease of triglycerides. Although the exact mechanism is unknown, a lot of studies showed that lipoprotein lipase stimulated via insulin reduces triglyceride values.
Aim: Our aim of the study is to prove the treatment benefits with fluids and intravenous rapid insulin in patients with type 2 diabetes and their role of decreasing the risk of acute pancreatitis due to high TG (above 5,6 mmol/L/500 mg/dL) and very high TG (above 11.3 mmol/L/1000 mg/dL), as a result of lipoprotein lipase activity.
Patients and methods: this is interventional follow-up study in 40 patients with hypertriglyceridemia, treated with fluids (Glucose 5%) and rapid insulin Aspart in infusion. All patie.. View More»
DOI:
10.35248/2155-6156.20.11.855
