Pure Green Pharmaceuticals, West Bloomfield, 48323, USA
Research Article
The Effects of Cannabidiol-Based Sublingual Tablets on Diabetic Neuropathic Pain
Author(s): Debra Kimless, Matthew K. Caloura*, Ara Kirakosyan and Stephen Goldner
Background: This is a prospective, open-label, drug and dose-controlled study. The primary objective of this study is to evaluate the safety and efficacy of cannabidiol (CBD) sublingual tablets for the treatment of patients with chronic diabetic neuropathic pain. The secondary objects are to evaluate the impact of CBD tablets on sleep quality and anxiety. We describe the effectiveness data at the completion of a 21-day study.
Methods: Subjects who met all inclusion/exclusion criteria and met the prespecified minimum Numerical Pain Rating Scale (NPRS) score were eligible for participation. Thirty-one subjects with chronic diabetic neuropathic pain were recruited. Patients were instructed to take CBD sublingual tablets three times a day and were taught to use a smart phone data collection application to record daily NPRS scores.
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