Cardiology Department, University of Lagos, Nigeria
Case Report
Stem Cell Therapy for Type 1 Diabetes Mellitus
Author(s): Sokolayam Ibrahim*
Background: Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease leading to the destruction of pancreatic beta cells and requiring lifelong insulin therapy. Stem cell therapy is a novel treatment approach aimed at regenerating or replacing damaged beta cells.
Case presentation: We report the case of a 25-year-old female with a 10- year history of poorly controlled T1DM despite intensive insulin therapy. The patient experienced frequent hypoglycemic episodes and early signs of diabetic complications.
Intervention: The patient underwent autologous hematopoietic stem cell transplantation (HSCT). Peripheral blood stem cells were mobilized using granulocyte-colony stimulating factor (G-CSF) and collected via apheresis. After conditioning with cyclophosphamide and antithymocyte globulin, the patient received the auto.. View More»
