Medical Affairs, Dr. Reddy's Laboratories Pvt Ltd, Ameerpet, Hyderabad, India
Research Article
Effect of High-Protein High-Fibre Supplement on Glycaemic Control in Overweight and Obese Indian Adults with Type 2 Diabetes Mellitus: A 24-Week, Randomized, Controlled Trial
Author(s): Rachana Bhoite*, Anitha Chandrasekaran, Shivani Aacharya, Amey Mane, Suyog Mehta, Ravindra Machhindra Kale, Gayathri Nagamuthu, Sasikala Selvara, Gayathri Rajagopal, Sudha Vasudevan, Anjana Ranjit Mohan, Ranjit Unnikrishnan, Kamala Krishnaswamy and Mohan Viswanathan
Background: Foods rich in protein, dietary fibre and low in glycaemic index could potentially improve glycaemic control and help in management of type 2 diabetes mellitus (T2DM) in overweight/obese participants. In this study, the effect of high-protein high-fibre (HPHF) nutritional supplement in addition to standard medical care for glycaemic control was evaluated.
Methods: In this open-label, parallel-arm, randomised study, 100 overweight/obese participants with T2DM (aged 30-65 years) were randomised (1:1) to either intervention group (25 g HPHF nutritional supplement [twice daily]+standard care of T2DM) or a control group (standard care of T2DM), for 6 months. Primary endpoint included change from baseline in 24â????hour glycaemic response at weeks 12 and 24.
Results: Of 320 participants screened, 100 par.. View More»
DOI:
10.35248/2155-6156.20.11.846
