National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Mississippi 38677, USA
Research Article
Linalool Glycosides from Flowers of Lantana montevidensis with Promising AntiInflammatory Potentials
Author(s): Mohamed NM, Malak LG and Ross SA*
Background and objective: Inflammation has been studied for thousands of years in an effort to mitigate its negative
effects on the body. Analgesic and anti-inflammatory drugs were the primary concern in monoterpenes.
Monoterpenes have been recognized for their ability to suppress inflammatory process and modulate the vital
chemical mediators of inflammation, such as pro-inflammatory and anti-inflammatory cytokines. This study aimed to
isolate the secondary metabolites of Lantana montevidensis (Verbenaceae) flowers and evaluate their in vitro antiinflammatory
activity.
Material and methods: Anti-inflammatory activity was done using TNF-α ELISA and NF-κB reporter gene assays.
Results and discussion: As a result, seven compounds were isolated and identified, in which three of them were.. View More»
