Department of Pediatrics, Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland
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A prospective cohort research used islet autoantibody testing to identify teenagers at risk for type1 diabetes and forecast the disease until young adulthood
Author(s): Rita Vejola*
This prospective cohort study aimed to evaluate the effectiveness of islet autoantibody screening in at-risk adolescents to predict the development of type 1 diabetes (T1D) until young adulthood. Type 1 diabetes is a chronic autoimmune disease that primarily affects young individuals and requires lifelong management of blood glucose levels. Early detection of T1D can facilitate timely intervention and improve health outcomes. A total of 500 at-risk adolescents were recruited based on genetic predisposition and family history and were regularly screened for islet autoantibodies [1, 2], including glutamic acid decarboxylase antibodies (GADA), insulinoma antigen-2 antibodies (IA-2A), and insulin autoantibodies (IAA). The screening process began during adolescence and continued until young adulthood. Among the cohort, 80 participants tested positive for one or more islet autoantibodies. O.. View More»
DOI:
10.35248/2155-6156.10001024
