Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Commentary
DNA Sequencing Which is based on Nucleobase-Specific Partial Chemical
Modification
Author(s): Rahul M. Kohli*
Maxim–Gilbert sequencing changed into the first widelyadopted method for DNA sequencing, and, at the side of theSanger dideoxy approach, represents the primary generation ofDNA sequencing methods. Maxim–Gilbert sequencing is nownot in giant use, having been supplanted with the aid ofsubsequent-technology sequencing methodsMaxam Gilbert
sequencing is described as a technique of DNA sequencing that'sbased on nuclease- specific partial chemical amendment of DNAand next of DNA cleavage. Nuclease is defined as compoundscontaining nitrogen agencies .. View More»
