Chemical Pathology Section, Medical Laboratory Services Department, Plateau State Specialist Hospital, Jos, Nigeria
Research Article
Predicting Diabetes in Relatives of Diabetic Patients Using Insulinoma Antigen-2 Antibody-A Biomarker for Type 1 Diabetes in Jos, Nigeria
Author(s): Bot DY*, Ahmed KM, Shindang J, Ekwempu A, Olaniru OB, Chundusu D, Bot SY, Mwantok EA, Pwajok PG, Ojo EO, Igwe O, Muhammad AA, Afolabi TA, Haladu A and Ezra K
Background: Type 1 diabetes is a chronic autoimmune disease caused by the destruction of insulin-secreting islet cells of the pancreas by several islet cell-specific autoantibodies that can be detected many months or years before the onset of diabetes. The presence of these antibodies can be attributed largely to environmental agents and also genetic factors. Knowing the frequency of these autoantibodies in a population is an important step for a better understanding, diagnosis and management of Type 1 diabetes. The aim of the research was to screen and identify those at greatest risk of diabetes (relatives of diabetic patients) early in life, as a precautionary step with the hope to deliver care in order to avoid the disease and its complications later in life.
Method: The study was conducted on eighty-eight apparently healthy young and ado.. View More»
DOI:
10.35248/2155-6156.19.10.831
