Department of Pharmacognosy, Assiut University, Assiut 71526, Egypt
Research Article
Linalool Glycosides from Flowers of Lantana montevidensis with Promising AntiInflammatory Potentials
Author(s): Mohamed NM, Malak LG and Ross SA*
Background and objective: Inflammation has been studied for thousands of years in an effort to mitigate its negative
effects on the body. Analgesic and anti-inflammatory drugs were the primary concern in monoterpenes.
Monoterpenes have been recognized for their ability to suppress inflammatory process and modulate the vital
chemical mediators of inflammation, such as pro-inflammatory and anti-inflammatory cytokines. This study aimed to
isolate the secondary metabolites of Lantana montevidensis (Verbenaceae) flowers and evaluate their in vitro antiinflammatory
activity.
Material and methods: Anti-inflammatory activity was done using TNF-α ELISA and NF-κB reporter gene assays.
Results and discussion: As a result, seven compounds were isolated and identified, in which three of them were.. View More»
