Department of Diabetes, Diabetes Institute University of Florida, United States
Research Article
Inflammatory Markers and the Impact of Weight Loss in Older Women with a History of Gestational Diabetes
Author(s): Michael Frano*
The goal of this study was to compare systemic inflammation between
older women with a history of gestational diabetes (GDM) and impaired
glucose tolerance (IGT) or type 2 diabetes (T2DM) and that between older
women with normal glucose tolerance (NGT), as well as to examine the
impact of weight loss (WL) brought on by diet and exercise training on
systemic inflammation and adipokine levels in these women. This was a
long-term clinical study of overweight or obese women (BMI: 32 kg/m2)
aged 59 years and older who had a history of GDM and either normal
glucose tolerance (NGT) or IGT/T2DM (). Women received VO2max, body
composition, blood sampling, glucose tolerance testing, and 2-hour
hyperinsulinemia-euglycemic clamps (40 mU m2 min) after completing 6
months of weight loss brought on by diet and activity. In the NGT group,
glucose utilisation (M) wa.. View More»
DOI:
10.35248/2155-6156.1000964