Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel 4031, Switzerland
Mini Review
The relationship between diabetes and oxidative stress, inflammation, and liver surgery
Author(s): Marc Donath* and Maria Catalina
Hyperglycemia and increased morbidity are hallmarks of diabetes mellitus
(DM), a metabolic condition that affects people all over the world. Increased
oxidative stress (OS) response and increased inflammatory response are
two of hyperglycemia's harmful effects. DM impairs the liver's capacity to
regenerate and is particularly linked to a poor prognosis after an injury
caused by ischaemia-reperfusion (I/R). This review aims to present recent
publications addressing the effects of DM (hyperglycaemia) on OS and the
inflammatory process, which play a crucial role in I/R injury and impaired
hepatic regeneration after liver surgery, in light of the growing need for
knowledge of the impact of DM on the liver following a surgical procedure. .. View More»
DOI:
10.35248/2155-6156.1000961