Department of Neurology, Affiliated Hospital of Shandong Medical College, Shandong, China
Research Article
Retrospective Study of Safety and Effectiveness of Levodopa in Patients with Parkinson’s Disease
Author(s): Linghui Wang* and Lei Xu
Levodopa has been widely used to treat symptoms of Parkinson’s Disease (PD); it is regarded as the most effective therapy for PD at present. Although the usage of levodopa rapidly increased with the number and health burden of PD in China, there is no systematic review to evaluate the efficiency and safety of levodopa in China mainland. Here, we retrospectively analyzed the efficiency and safety of PD treatment using levodopa in Affiliated Hospital of Shandong Medical College during the last decade (2010-2020). A total of 432 patients were included in the present study, with all patients completed at least 24 weeks of levodopa treatment. Unified Parkinson’s Disease Rating Scale (UPDRS) and Hamilton Depression Rating Scale (HAMD) were used to evaluate the drug efficacy and management of affective disorder after levodopa treatment, respectively, while any adverse effects of .. View More»
