Editorial Office, Journal of Forensic Pathology, United Kingdom
Editorial
Reassessing The Cause of Death In Clinical Research
Author(s): Joanna Grace*
The direct examination of brain tissue in people with autism and similar illnesses is made possible by post-mortem investigations. There have been a number of review publications that have concentrated on certain post-mortem anomalies, but none that have compiled all of the post-mortem literature. Here, we conduct a thorough evaluation of the data from post-mortem investigations into autism and other illnesses that exhibit autistic symptoms. A few strikingly consistent conclusions are apparent despite the literature's short number of research and tiny sample sizes. Although there are constant changes in minicolumn numbers and abnormal myelination, cortical layering is essentially unaffected. Transcriptomics frequently links dysfunctional metabolic, apoptotic, proliferation, and immunological processes. Non-coding RNA, abnormal epigenetic profiles, GABAergic, glutamatergic, and gli.. View More»
DOI:
10.35248 2648 1312.22.7(1).117
