Medical College and Hospital, Chandigarh, India
Value Added Abstract
Evaluation of efficacy and safety of oral terbinafine and itraconazole combination therapy in the management of dermatophytosis
Author(s): Priyanka Sharma*, Mala Bhalla, Gurvinder P Thami and Jagdish Chander
Background: Dermatophytosis represents one of the most common dermatological diseases affecting 20-25% of the world’s population, with a rapid upsurge in atypical cases with bizarre clinical as well as therapeutic behaviour in the recent years worldwide. The conventional treatment guidelines seem to fail tremendously in the management of these infections and current treatment approach is largely subjective and experience based.
Objective: To evaluate the efficacy and safety of oral terbinafine and itraconazole combination therapy in the management of dermatophytosis.
Methods: Clinically diagnosed and KOH positive patients of tinea corporis/cruris/faciei were randomly divided into three groups and given terbinafine 250 mg, itraconazole 200 mg and a combination of both once daily taken on the same day respectively .. View More»
