Department of Zoology, university of Sialkot Punjab, Pakistan
Research Article
Antidiabetic Effect of Scorpion Venom (Hottentota tamulus and Androctonus finitimus) using alloxan induced diabetic mice model
Author(s): Saadia Tobassum* and Farah Liaqat*
The antidiabetic effect of venom of Hottentota tamulus and Androctonus finitimus scorpions was evaluated in the alloxan-induced diabetic mice by studying biological parameters and pancreas structure abnormalities. Diabetes is a metabolic disorder characterized by elevated blood glucose levels due to either insufficient insulin production (Type 1) or impaired insulin function (Type 2), leading to various health complications. For extraction of venom, 50 scorpions of Hottentota tamulus and Androctonus finitimus species were maintained in the lab. Venom of both species was characterized and its effect was evaluated on diabetes. In this study, 32 male albino mice were divided into eight main groups each of 4 mice. Group 1 was injected intraperitoneally with physiological saline solution, Group 2 was given alloxan but no treatment was given. Group 3 received crude venom (150 mg/kg) (i p., .. View More»
DOI:
10.35248/2155-6156.10001058
