Department of Organic Chemistry, University of Yaoundé I, Cameroon
Research Article
Isolation and Characterization of Chemical Constituents from the Crude mExtracts of Crossopteryx Febrifuga (Afzel ex g. don) benth (Rubiaceae) and Evaluation of Their Phytotoxicity and Antioxidant Activity
Author(s): Bealem Aristide, Sakava Paul*, Lidia Favier, Didier Hauchard, Jean-Paul Guegan, Nyemb Jean Noël, Talla Emmanuel, Celine Henoumont, Sophie Laurent, Atchade De Theodore Alex and Mbafor Tanyi Joseph
The aim of this work is to isolate, characterize, and evaluate the antioxidant activity as well as the phytotoxicity of crude extracts and compounds obtained from C. febrifuga. Nine compounds were isolated from leaves, stem bark and roots (methylene chloride/methanol:1/1) crude extracts after repeated silica gel column chromatography corresponding to shanzhiside methyl ester (1), D-mannitol (2), a mixture of two isomeric pentacyclic triterpenes: oleanolic acid (3a) and ursolic acid (3b), 11-methylixoside (4), 3β-urs-12, 20(30)-diene-27,28-dioic acid (5), quinovin glycoside C (6), 3-O-β-D-3-oxo-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (7) and 3β-(-α-Lrhamnopyranosyloxy)-ursa-12,20(30)-diene-27,28-dioic acid (8). The compound chemical structures were established by studying their 1H and 13C NMR (1D and 2D) and Mass Spectrometry (MS) spectra. The antioxid.. View More»
DOI:
10.35248/2329-6836.21.9.416
