Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy
Perspective
Unraveling the Interplay between Cholesterol Metabolism, Pancreatic ?-Cell Function, and Diabetes
Author(s): Albert Catapano*
Cholesterol metabolism, once primarily associated with cardiovascular health, has emerged as a multifaceted player in various physiological processes, including pancreatic β-cell function. This article delves into the intricate connections between cholesterol metabolism, insulinsecreting pancreatic β-cells, and the pathogenesis of diabetes. From cholesterol's role in membrane fluidity to its impact on insulin secretion and intracellular signaling, this review explores the multifaceted interplay that positions cholesterol as a potential regulator of pancreatic β-cell health. Understanding these interactions offers insights into diabetes pathogenesis and uncovers novel avenues for therapeutic interventions [1]... View More»
DOI:
10.35248/2155-6156.10001033
