Cystic fibrosis (CF) is a complex genetic disorder affecting multiple organ systems, including the pancreas. Lung transplantation often provides a new lease of life to CF patients, yet it can also unveil underlying glucose metabolism abnormalities. This study investigates the distinctive glucoserelated challenges faced by adult CF patients post-lung transplantation. Markedly delayed insulin secretion and a surprisingly high rate of undetected overt diabetes characterize the altered glucose metabolism in this population [1]. The study emphasizes the need for vigilant glucose monitoring and tailored interventions to mitigate the impact of posttransplant metabolic disturbances.