This study investigates the phenomenon of relative protection against the transmission of Type-1 diabetes mellitus (T1DM) from mothers to their offspring. Despite the hereditary nature of T1DM, epidemiological evidence suggests that maternal inheritance may confer a degree of resistance or protection against the development of T1DM in children. This abstract explores the mechanisms underlying this phenomenon and examines the implications for understanding the pathogenesis of T1DM and developing preventive strategies.
