Hassan A. Saad*, Azza Baz, Mohamed Riad, Mohamed E Eraky, Mohamed I Farid and Khaled Sharaf
An elevated risk of mortality, secondary sarcopenia, multiorgan dysfunction, sepsis, and severe oxidative stress are all brought on by major burn injuries. They also set off a systemic inflammatory response and a chronic hypermetabolic and hypercatabolic state. Following heat damage, poor clinical outcomes have been linked to calorie shortfalls, negative protein balance, and antioxidant micronutrient insufficiency. In this situation, early enteral feeding at the onset of resuscitation, together with tailored nutrition therapy, is recommended. Various pharmacological and dietary therapies targeting immunological and metabolic response modulation have been studied during the past 40 years. In this patient population, these tactics have demonstrated the ability to reduce acute malnutrition, control the immunoinflammatory response, and enhance pertinent clinical outcomes. Summarising the most recent research on nutrition therapy and metabolic response in critically ill burn patients is the aim of this updated review.
